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Removal of AU Bias from Microarray mRNA Expression Data Enhances Computational Identification of Active MicroRNAs

Elucidation of regulatory roles played by microRNAs (miRs) in various biological networks is one of the greatest challenges of present molecular and computational biology. The integrated analysis of gene expression data and 3′-UTR sequences holds great promise for being an effective means to systema...

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Detalles Bibliográficos
Autores principales: Elkon, Ran, Agami, Reuven
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2533120/
https://www.ncbi.nlm.nih.gov/pubmed/18833292
http://dx.doi.org/10.1371/journal.pcbi.1000189