Genomic analysis of the TRIM family reveals two groups of genes with distinct evolutionary properties

BACKGROUND: The TRIM family is composed of multi-domain proteins that display the Tripartite Motif (RING, B-box and Coiled-coil) that can be associated with a C-terminal domain. TRIM genes are involved in ubiquitylation and are implicated in a variety of human pathologies, from Mendelian inherited d...

Descripción completa

Detalles Bibliográficos
Autores principales: Sardiello, Marco, Cairo, Stefano, Fontanella, Bianca, Ballabio, Andrea, Meroni, Germana
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2533329/
https://www.ncbi.nlm.nih.gov/pubmed/18673550
http://dx.doi.org/10.1186/1471-2148-8-225

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2533329/
https://www.ncbi.nlm.nih.gov/pubmed/18673550
http://dx.doi.org/10.1186/1471-2148-8-225

Ejemplares similares