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Hydrogen bond networks determine emergent mechanical and thermodynamic properties across a protein family

BACKGROUND: Gram-negative bacteria use periplasmic-binding proteins (bPBP) to transport nutrients through the periplasm. Despite immense diversity within the recognized substrates, all members of the family share a common fold that includes two domains that are separated by a conserved hinge. The hi...

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Detalles Bibliográficos
Autores principales: Livesay, Dennis R, Huynh, Dang H, Dallakyan, Sargis, Jacobs, Donald J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2533333/
https://www.ncbi.nlm.nih.gov/pubmed/18700034
http://dx.doi.org/10.1186/1752-153X-2-17