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Association between umbilical cord glucocorticoids and blood pressure at age 3 years

BACKGROUND: Animal data show that decreased activity of placental 11-beta-hydroxysteroid dehydrogenase type 2 (11β-HSD2), which potently inactivates glucocorticoids (e.g. cortisol) to inert forms (cortisone), allows increased access of maternal glucocorticoids to the fetus and 'programs' h...

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Detalles Bibliográficos
Autores principales: Huh, Susanna Y, Andrew, Ruth, Rich-Edwards, Janet W, Kleinman, Ken P, Seckl, Jonathan R, Gillman, Matthew W
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2533350/
https://www.ncbi.nlm.nih.gov/pubmed/18755017
http://dx.doi.org/10.1186/1741-7015-6-25