Highly specific inhibition of leukaemia virus membrane fusion by interaction of peptide antagonists with a conserved region of the coiled coil of envelope

BACKGROUND: Human T-cell leukaemia virus (HTLV-1) and bovine leukaemia virus (BLV) entry into cells is mediated by envelope glycoprotein catalyzed membrane fusion and is achieved by folding of the transmembrane glycoprotein (TM) from a rod-like pre-hairpin intermediate to a trimer-of-hairpins. For H...

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Detalles Bibliográficos
Autores principales: Lamb, Daniel, Schüttelkopf, Alexander W, van Aalten, Daan MF, Brighty, David W
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2533354/
https://www.ncbi.nlm.nih.gov/pubmed/18680566
http://dx.doi.org/10.1186/1742-4690-5-70

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2533354/
https://www.ncbi.nlm.nih.gov/pubmed/18680566
http://dx.doi.org/10.1186/1742-4690-5-70

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