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DHA induces ER stress and growth arrest in human colon cancer cells: associations with cholesterol and calcium homeostasis

Polyunsaturated fatty acids (PUFAs) are normal constituents of the diet, but have properties different from other fatty acids (e.g., through generation of signaling molecules). N-3 PUFAs reduce cancer cell growth, but no unified mechanism has been identified. We show that docosahexaenoic acid (DHA;...

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Detalles Bibliográficos
Autores principales: Jakobsen, Caroline Hild, Størvold, Gro Leite, Bremseth, Hilde, Follestad, Turid, Sand, Kristin, Mack, Merete, Olsen, Karina Standahl, Lundemo, Anne Gøril, Iversen, Jens Gustav, Krokan, Hans Einar, Schønberg, Svanhild Arentz
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2533412/
https://www.ncbi.nlm.nih.gov/pubmed/18566476
http://dx.doi.org/10.1194/jlr.M700389-JLR200