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Neuroprotective effects of edaravone-administration on 6-OHDA-treated dopaminergic neurons

BACKGROUND: Parkinson's disease (PD) is a neurological disorder characterized by the degeneration of nigrostriatal dopaminergic systems. Free radicals induced by oxidative stress are involved in the mechanisms of cell death in PD. This study clarifies the neuroprotective effects of edaravone (M...

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Detalles Bibliográficos
Autores principales: Ji Yuan, Wen, Yasuhara, Takao, Shingo, Tetsuro, Muraoka, Kenichiro, Agari, Takashi, Kameda, Masahiro, Uozumi, Takashi, Tajiri, Naoki, Morimoto, Takamasa, Jing, Meng, Baba, Tanefumi, Wang, Feifei, Leung, Hanbai, Matsui, Toshihiro, Miyoshi, Yasuyuki, Date, Isao
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2533664/
https://www.ncbi.nlm.nih.gov/pubmed/18671880
http://dx.doi.org/10.1186/1471-2202-9-75