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TSG-6 Regulates Bone Remodeling through Inhibition of Osteoblastogenesis and Osteoclast Activation

TSG-6 is an inflammation-induced protein that is produced at pathological sites, including arthritic joints. In animal models of arthritis, TSG-6 protects against joint damage; this has been attributed to its inhibitory effects on neutrophil migration and plasmin activity. Here we investigated wheth...

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Detalles Bibliográficos
Autores principales: Mahoney, David J., Mikecz, Katalin, Ali, Tariq, Mabilleau, Guillaume, Benayahu, Dafna, Plaas, Anna, Milner, Caroline M., Day, Anthony J., Sabokbar, Afsaneh
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2533787/
https://www.ncbi.nlm.nih.gov/pubmed/18586671
http://dx.doi.org/10.1074/jbc.M802138200