Cargando…

Characterization of the p53 Response to Oncogene-Induced Senescence

BACKGROUND: P53 activation can trigger various outcomes, among them reversible growth arrest or cellular senescence. It is a live debate whether these outcomes are influenced by quantitative or qualitative mechanisms. Furthermore, the relative contribution of p53 to Ras-induced senescence is also ma...

Descripción completa

Detalles Bibliográficos
Autores principales: Ruiz, Lidia, Traskine, Magali, Ferrer, Irene, Castro, Estrella, Leal, Juan F. M., Kaufman, Marcelline, Carnero, Amancio
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2535567/
https://www.ncbi.nlm.nih.gov/pubmed/18800172
http://dx.doi.org/10.1371/journal.pone.0003230