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Fluoride Induces Endoplasmic Reticulum Stress and Inhibits Protein Synthesis and Secretion
BACKGROUND: Exposure to excessive amounts of fluoride (F(−)) causes dental fluorosis in susceptible individuals; however, the mechanism of F(−)-induced toxicity is unclear. Previously, we have shown that high-dose F(−) activates the unfolded protein response (UPR) in ameloblasts that are responsible...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
National Institute of Environmental Health Sciences
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2535613/ https://www.ncbi.nlm.nih.gov/pubmed/18795154 http://dx.doi.org/10.1289/ehp.11375 |