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A Genome-Wide RNAi Screen to Dissect Centriole Duplication and Centrosome Maturation in Drosophila

Centrosomes comprise a pair of centrioles surrounded by an amorphous pericentriolar material (PCM). Here, we have performed a microscopy-based genome-wide RNA interference (RNAi) screen in Drosophila cells to identify proteins required for centriole duplication and mitotic PCM recruitment. We analys...

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Detalles Bibliográficos
Autores principales: Dobbelaere, Jeroen, Josué, Filipe, Suijkerbuijk, Saskia, Baum, Buzz, Tapon, Nicolas, Raff, Jordan
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2535660/
https://www.ncbi.nlm.nih.gov/pubmed/18798690
http://dx.doi.org/10.1371/journal.pbio.0060224