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Constructing disease-specific gene networks using pair-wise relevance metric: Application to colon cancer identifies interleukin 8, desmin and enolase 1 as the central elements

BACKGROUND: With the advance of large-scale omics technologies, it is now feasible to reversely engineer the underlying genetic networks that describe the complex interplays of molecular elements that lead to complex diseases. Current networking approaches are mainly focusing on building genetic net...

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Detalles Bibliográficos
Autores principales: Jiang, Wei, Li, Xia, Rao, Shaoqi, Wang, Lihong, Du, Lei, Li, Chuanxing, Wu, Chao, Wang, Hongzhi, Wang, Yadong, Yang, Baofeng
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2535780/
https://www.ncbi.nlm.nih.gov/pubmed/18691435
http://dx.doi.org/10.1186/1752-0509-2-72