Cargando…

Selective inhibition of yeast regulons by daunorubicin: A transcriptome-wide analysis

BACKGROUND: The antitumor drug daunorubicin exerts some of its cytotoxic effects by binding to DNA and inhibiting the transcription of different genes. We analysed this effect in vivo at the transcriptome level using the budding yeast Saccharomyces cerevisiae as a model and sublethal (IC(40)) concen...

Descripción completa

Detalles Bibliográficos
Autores principales: Rojas, Marta, Casado, Marta, Portugal, José, Piña, Benjamin
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2536678/
https://www.ncbi.nlm.nih.gov/pubmed/18667070
http://dx.doi.org/10.1186/1471-2164-9-358