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Selective inhibition of yeast regulons by daunorubicin: A transcriptome-wide analysis
BACKGROUND: The antitumor drug daunorubicin exerts some of its cytotoxic effects by binding to DNA and inhibiting the transcription of different genes. We analysed this effect in vivo at the transcriptome level using the budding yeast Saccharomyces cerevisiae as a model and sublethal (IC(40)) concen...
Autores principales: | Rojas, Marta, Casado, Marta, Portugal, José, Piña, Benjamin |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2536678/ https://www.ncbi.nlm.nih.gov/pubmed/18667070 http://dx.doi.org/10.1186/1471-2164-9-358 |
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