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Predicting Quantitative Genetic Interactions by Means of Sequential Matrix Approximation

Despite the emerging experimental techniques for perturbing multiple genes and measuring their quantitative phenotypic effects, genetic interactions have remained extremely difficult to predict on a large scale. Using a recent high-resolution screen of genetic interactions in yeast as a case study,...

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Detalles Bibliográficos
Autores principales: Järvinen, Aki P., Hiissa, Jukka, Elo, Laura L., Aittokallio, Tero
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2538561/
https://www.ncbi.nlm.nih.gov/pubmed/18818762
http://dx.doi.org/10.1371/journal.pone.0003284