Molecular recognition of nitrated fatty acids by PPARγ

Peroxisome proliferator activated receptor-γ (PPARγ) regulates metabolic homeostasis and adipocyte differentiation, and it is activated by oxidized and nitrated fatty acids. Here we report the crystal structure of the PPARγ ligand binding domain bound to nitrated linoleic acid, a potent endogenous l...

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Detalles Bibliográficos
Autores principales: Li, Yong, Zhang, Jifeng, Schopfer, Francisco J, Martynowski, Dariusz, Garcia-Barrio, Minerva T, Kovach, Amanda, Suino-Powell, Kelly, Baker, Paul R S, Freeman, Bruce A, Chen, Y Eugene, Xu, H Eric
Formato: Texto
Lenguaje:English
Publicado: 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2538624/
https://www.ncbi.nlm.nih.gov/pubmed/18604218
http://dx.doi.org/10.1038/nsmb.1447

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2538624/
https://www.ncbi.nlm.nih.gov/pubmed/18604218
http://dx.doi.org/10.1038/nsmb.1447

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