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Constraints imposed by non-functional protein–protein interactions on gene expression and proteome size
Crowded intracellular environments present a challenge for proteins to form functional specific complexes while reducing non-functional interactions with promiscuous non-functional partners. Here we show how the need to minimize the waste of resources to non-functional interactions limits the proteo...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2538908/ https://www.ncbi.nlm.nih.gov/pubmed/18682700 http://dx.doi.org/10.1038/msb.2008.48 |