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Metabolic profiling of the human response to a glucose challenge reveals distinct axes of insulin sensitivity

Glucose ingestion after an overnight fast triggers an insulin-dependent, homeostatic program that is altered in diabetes. The full spectrum of biochemical changes associated with this transition is currently unknown. We have developed a mass spectrometry-based strategy to simultaneously measure 191...

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Detalles Bibliográficos
Autores principales: Shaham, Oded, Wei, Ru, Wang, Thomas J, Ricciardi, Catherine, Lewis, Gregory D, Vasan, Ramachandran S, Carr, Steven A, Thadhani, Ravi, Gerszten, Robert E, Mootha, Vamsi K
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2538910/
https://www.ncbi.nlm.nih.gov/pubmed/18682704
http://dx.doi.org/10.1038/msb.2008.50