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Metabolic profiling of the human response to a glucose challenge reveals distinct axes of insulin sensitivity
Glucose ingestion after an overnight fast triggers an insulin-dependent, homeostatic program that is altered in diabetes. The full spectrum of biochemical changes associated with this transition is currently unknown. We have developed a mass spectrometry-based strategy to simultaneously measure 191...
Autores principales: | Shaham, Oded, Wei, Ru, Wang, Thomas J, Ricciardi, Catherine, Lewis, Gregory D, Vasan, Ramachandran S, Carr, Steven A, Thadhani, Ravi, Gerszten, Robert E, Mootha, Vamsi K |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2538910/ https://www.ncbi.nlm.nih.gov/pubmed/18682704 http://dx.doi.org/10.1038/msb.2008.50 |
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