The Netrin-related domain of Sfrp1 interacts with Wnt ligands and antagonizes their activity in the anterior neural plate

BACKGROUND: Secreted frizzled related proteins (SFRPs) are multifunctional modulators of Wnt and BMP (Bone Morphogenetic Protein) signalling necessary for the development of most organs and the homeostasis of different adult tissues. SFRPs fold in two independent domains: the cysteine rich domain (S...

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Detalles Bibliográficos
Autores principales: Lopez-Rios, Javier, Esteve, Pilar, Ruiz, Jose Maria, Bovolenta, Paola
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2542364/
https://www.ncbi.nlm.nih.gov/pubmed/18715500
http://dx.doi.org/10.1186/1749-8104-3-19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2542364/
https://www.ncbi.nlm.nih.gov/pubmed/18715500
http://dx.doi.org/10.1186/1749-8104-3-19

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