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B Cell Recognition of the Conserved HIV-1 Co-Receptor Binding Site Is Altered by Endogenous Primate CD4

The surface HIV-1 exterior envelope glycoprotein, gp120, binds to CD4 on the target cell surface to induce the co-receptor binding site on gp120 as the initial step in the entry process. The binding site is comprised of a highly conserved region on the gp120 core, as well as elements of the third va...

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Detalles Bibliográficos
Autores principales: Forsell, Mattias N. E., Dey, Barna, Mörner, Andreas, Svehla, Krisha, O'dell, Sijy, Högerkorp, Carl-Magnus, Voss, Gerald, Thorstensson, Rigmor, Shaw, George M., Mascola, John R., Karlsson Hedestam, Gunilla B., Wyatt, Richard T.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2542413/
https://www.ncbi.nlm.nih.gov/pubmed/18833294
http://dx.doi.org/10.1371/journal.ppat.1000171