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Context-Dependent Requirement for dE2F during Oncogenic Proliferation
The Hippo pathway negatively regulates the cell number in epithelial tissue. Upon its inactivation, an excess of cells is produced. These additional cells are generated from an increased rate of cell division, followed by inappropriate proliferation of cells that have failed to exit the cell cycle....
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2542417/ https://www.ncbi.nlm.nih.gov/pubmed/18833298 http://dx.doi.org/10.1371/journal.pgen.1000205 |