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Direct role of dynein motor in stable kinetochore-microtubule attachment, orientation, and alignment

Cytoplasmic dynein has been implicated in diverse mitotic functions, several involving its association with kinetochores. Much of the supporting evidence comes from inhibition of dynein regulatory factors. To obtain direct insight into kinetochore dynein function, we expressed a series of dynein tai...

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Detalles Bibliográficos
Autores principales: Varma, Dileep, Monzo, Pascale, Stehman, Stephanie A., Vallee, Richard B.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2542467/
https://www.ncbi.nlm.nih.gov/pubmed/18809721
http://dx.doi.org/10.1083/jcb.200710106