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Association between active genes occurs at nuclear speckles and is modulated by chromatin environment

Genes on different chromosomes can be spatially associated in the nucleus in several transcriptional and regulatory situations; however, the functional significance of such associations remains unclear. Using human erythropoiesis as a model, we show that five cotranscribed genes, which are found on...

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Detalles Bibliográficos
Autores principales: Brown, Jill M., Green, Joanne, das Neves, Ricardo Pires, Wallace, Helen A.C., Smith, Andrew J.H., Hughes, Jim, Gray, Nicki, Taylor, Steve, Wood, William G., Higgs, Douglas R., Iborra, Francisco J., Buckle, Veronica J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2542471/
https://www.ncbi.nlm.nih.gov/pubmed/18809724
http://dx.doi.org/10.1083/jcb.200803174