Cargando…
Association between active genes occurs at nuclear speckles and is modulated by chromatin environment
Genes on different chromosomes can be spatially associated in the nucleus in several transcriptional and regulatory situations; however, the functional significance of such associations remains unclear. Using human erythropoiesis as a model, we show that five cotranscribed genes, which are found on...
Autores principales: | Brown, Jill M., Green, Joanne, das Neves, Ricardo Pires, Wallace, Helen A.C., Smith, Andrew J.H., Hughes, Jim, Gray, Nicki, Taylor, Steve, Wood, William G., Higgs, Douglas R., Iborra, Francisco J., Buckle, Veronica J. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2008
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2542471/ https://www.ncbi.nlm.nih.gov/pubmed/18809724 http://dx.doi.org/10.1083/jcb.200803174 |
Ejemplares similares
-
Coregulated human globin genes are frequently in spatial proximity when active
por: Brown, Jill M., et al.
Publicado: (2006) -
Single-allele chromatin interactions identify regulatory hubs in dynamic compartmentalized domains
por: Oudelaar, A. Marieke, et al.
Publicado: (2018) -
A tissue-specific self-interacting chromatin domain forms independently of enhancer-promoter interactions
por: Brown, Jill M., et al.
Publicado: (2018) -
Osmotic modulation of chromatin impacts on efficiency and kinetics of cell fate modulation
por: Lima, A. F., et al.
Publicado: (2018) -
Insulator speckles associated with long-distance chromatin contacts
por: Buxa, Melanie K., et al.
Publicado: (2016)