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NCAM induces CaMKIIα-mediated RPTPα phosphorylation to enhance its catalytic activity and neurite outgrowth

Receptor protein tyrosine phosphatase α (RPTPα) phosphatase activity is required for intracellular signaling cascades that are activated in motile cells and growing neurites. Little is known, however, about mechanisms that coordinate RPTPα activity with cell behavior. We show that clustering of neur...

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Detalles Bibliográficos
Autores principales: Bodrikov, Vsevolod, Sytnyk, Vladimir, Leshchyns'ka, Iryna, den Hertog, Jeroen, Schachner, Melitta
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2542478/
https://www.ncbi.nlm.nih.gov/pubmed/18809727
http://dx.doi.org/10.1083/jcb.200803045