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Var2CSA DBL6-epsilon domain expressed in HEK293 induces limited cross-reactive and blocking antibodies to CSA binding parasites

BACKGROUND: Pregnancy-associated malaria (PAM) is a serious consequence of Plasmodium falciparum-infected erythrocytes sequestration in the placenta through the adhesion to the placental receptor chondroitin sulfate A (CSA). Although women become resistant to PAM as they acquire transcending inhibit...

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Detalles Bibliográficos
Autores principales: Fernandez, Pablo, KViebig, Nicola, Dechavanne, Sébastien, Lépolard, Catherine, Gysin, Jürg, Scherf, Artur, Gamain, Benoit
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2543044/
https://www.ncbi.nlm.nih.gov/pubmed/18771584
http://dx.doi.org/10.1186/1475-2875-7-170