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Promoter methylation inhibits BRD7 expression in human nasopharyngeal carcinoma cells

BACKGROUND: Nasopharyngeal carcinoma (NPC) is a head and neck malignancy with high occurrence in South-East Asia and Southern China. Recent findings suggest that epigenetic inactivation of multiple tumor suppressor genes plays an important role in the tumourigenesis of NPC. BRD7 is a NPC-associated...

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Detalles Bibliográficos
Autores principales: Liu, Huaying, Zhang, Liming, Niu, Zhaoxia, Zhou, Ming, Peng, Cong, Li, Xiayu, Deng, Tan, Shi, Lei, Tan, Yixin, Li, Guiyuan
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2543047/
https://www.ncbi.nlm.nih.gov/pubmed/18778484
http://dx.doi.org/10.1186/1471-2407-8-253