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Cingulate NMDA NR2B receptors contribute to morphine-induced analgesic tolerance

Morphine is widely used to treat chronic pain, however its utility is hindered by the development of tolerance to its analgesic effects. While N-methyl-D-aspartate (NMDA) receptors are known to play roles in morphine tolerance and dependence, less is known about the roles of individual NMDA receptor...

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Detalles Bibliográficos
Autores principales: Ko, Shanelle W, Wu, Long-Jun, Shum, Fanny, Quan, Jessica, Zhuo, Min
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2546399/
https://www.ncbi.nlm.nih.gov/pubmed/18803856
http://dx.doi.org/10.1186/1756-6606-1-2