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SLEPR: A Sample-Level Enrichment-Based Pathway Ranking Method — Seeking Biological Themes through Pathway-Level Consistency

Analysis of microarray and other high throughput data often involves identification of genes consistently up or down-regulated across samples as the first step in extraction of biological meaning. This gene-level paradigm can be limited as a result of valid sample fluctuations and biological complex...

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Detalles Bibliográficos
Autores principales: Yi, Ming, Stephens, Robert M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2546449/
https://www.ncbi.nlm.nih.gov/pubmed/18818771
http://dx.doi.org/10.1371/journal.pone.0003288