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GPCRTree: online hierarchical classification of GPCR function

BACKGROUND: G protein-coupled receptors (GPCRs) play important physiological roles transducing extracellular signals into intracellular responses. Approximately 50% of all marketed drugs target a GPCR. There remains considerable interest in effectively predicting the function of a GPCR from its prim...

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Bibliographic Details
Main Authors: Davies, Matthew N, Secker, Andrew, Halling-Brown, Mark, Moss, David S, Freitas, Alex A, Timmis, Jon, Clark, Edward, Flower, Darren R
Format: Text
Language:English
Published: BioMed Central 2008
Subjects:
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2547103/
https://www.ncbi.nlm.nih.gov/pubmed/18717986
http://dx.doi.org/10.1186/1756-0500-1-67