Haplotype block partitioning as a tool for dimensionality reduction in SNP association studies

BACKGROUND: Identification of disease-related genes in association studies is challenged by the large number of SNPs typed. To address the dilution of power caused by high dimensionality, and to generate results that are biologically interpretable, it is critical to take into consideration spatial c...

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Detalles Bibliográficos
Autores principales: Pattaro, Cristian, Ruczinski, Ingo, Fallin, Danièle M, Parmigiani, Giovanni
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2547855/
https://www.ncbi.nlm.nih.gov/pubmed/18759977
http://dx.doi.org/10.1186/1471-2164-9-405

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2547855/
https://www.ncbi.nlm.nih.gov/pubmed/18759977
http://dx.doi.org/10.1186/1471-2164-9-405

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