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Haplotype block partitioning as a tool for dimensionality reduction in SNP association studies
BACKGROUND: Identification of disease-related genes in association studies is challenged by the large number of SNPs typed. To address the dilution of power caused by high dimensionality, and to generate results that are biologically interpretable, it is critical to take into consideration spatial c...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2547855/ https://www.ncbi.nlm.nih.gov/pubmed/18759977 http://dx.doi.org/10.1186/1471-2164-9-405 |