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Streptococcus pneumoniae stabilizes tumor necrosis factor α mRNA through a pathway dependent on p38 MAPK but independent of Toll-like receptors

BACKGROUND: Streptococcus pneumoniae is a human pathogenic bacteria and a major cause of severe invasive diseases, including pneumonia, bacteremia, and meningitis. Infections with S. pneumoniae evoke a strong inflammatory response, which plays a major role in the pathogenesis of pneumococcal disease...

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Detalles Bibliográficos
Autores principales: Mogensen, Trine H, Berg, Randi S, Østergaard, Lars, Paludan, Søren R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2551578/
https://www.ncbi.nlm.nih.gov/pubmed/18796140
http://dx.doi.org/10.1186/1471-2172-9-52