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Primer sets for cloning the human repertoire of T cell Receptor Variable regions

BACKGROUND: Amplification and cloning of naïve T cell Receptor (TR) repertoires or antigen-specific TR is crucial to shape immune response and to develop immuno-based therapies. TR variable (V) regions are encoded by several genes that recombine during T cell development. The cloning of expressed ge...

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Detalles Bibliográficos
Autores principales: Boria, Ilenia, Cotella, Diego, Dianzani, Irma, Santoro, Claudio, Sblattero, Daniele
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2551579/
https://www.ncbi.nlm.nih.gov/pubmed/18759974
http://dx.doi.org/10.1186/1471-2172-9-50