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Primer sets for cloning the human repertoire of T cell Receptor Variable regions
BACKGROUND: Amplification and cloning of naïve T cell Receptor (TR) repertoires or antigen-specific TR is crucial to shape immune response and to develop immuno-based therapies. TR variable (V) regions are encoded by several genes that recombine during T cell development. The cloning of expressed ge...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2551579/ https://www.ncbi.nlm.nih.gov/pubmed/18759974 http://dx.doi.org/10.1186/1471-2172-9-50 |