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MAP kinase pathways and calcitonin influence CD44 alternate isoform expression in prostate cancer cells

BACKGROUND: Dysregulated expression and splicing of cell adhesion marker CD44 is found in many types of cancer. In prostate cancer (PC) specifically, the standard isoform (CD44s) has been found to be downregulated compared with benign tissue whereas predominant variant isoform CD44v7-10 is upregulat...

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Detalles Bibliográficos
Autores principales: Robbins, Eric W, Travanty, Emily A, Yang, Kui, Iczkowski, Kenneth A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2551621/
https://www.ncbi.nlm.nih.gov/pubmed/18793421
http://dx.doi.org/10.1186/1471-2407-8-260