Impact of BRAF, MLH1 on the incidence of microsatellite instability high colorectal cancer in populations based study

We have identified an alternative pathway of tumorigenesis in sporadic colon cancer, involving microsatellite instability due to mismatched repair methylation, which may be driven by mutations in the BRAF gene (V600E). Colorectal cancer (CRC) is the most common cancer in the world, and African Ameri...

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Detalles Bibliográficos
Autores principales: Brim, Hassan, Mokarram, Pooneh, Naghibalhossaini, Fakhraddin, Saberi-Firoozi, Mehdi, Al-Mandhari, Mansour, Al-Mawaly, Kamla, Al-Mjeni, Rayhaneh, Al-Sayegh, Abeer, Raeburn, Sandy, Lee, Edward, Giardiello, Francis, Smoot, Duane T, Vilkin, Alexander, Boland, C Richard, Goel, Ajay, Hafezi, Mitra, Nouraie, Mehdi, Ashktorab, Hassan
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2551625/
https://www.ncbi.nlm.nih.gov/pubmed/18718023
http://dx.doi.org/10.1186/1476-4598-7-68

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2551625/
https://www.ncbi.nlm.nih.gov/pubmed/18718023
http://dx.doi.org/10.1186/1476-4598-7-68

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