miR-375 Targets 3′-Phosphoinositide–Dependent Protein Kinase-1 and Regulates Glucose-Induced Biological Responses in Pancreatic β-Cells

OBJECTIVE—MicroRNAs are short, noncoding RNAs that regulate gene expression. We hypothesized that the phosphatidylinositol 3-kinase (PI 3-kinase) cascade known to be important in β-cell physiology could be regulated by microRNAs. Here, we focused on the pancreas-specific miR-375 as a potential regul...

Descripción completa

Detalles Bibliográficos
Autores principales: El Ouaamari, Abdelfattah, Baroukh, Nadine, Martens, Geert A., Lebrun, Patricia, Pipeleers, Daniel, van Obberghen, Emmanuel
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2008
Materias:
Islet Studies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2551681/
https://www.ncbi.nlm.nih.gov/pubmed/18591395
http://dx.doi.org/10.2337/db07-1614

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2551681/
https://www.ncbi.nlm.nih.gov/pubmed/18591395
http://dx.doi.org/10.2337/db07-1614

Ejemplares similares