Inducible Overexpression of sFlt-1 in Podocytes Ameliorates Glomerulopathy in Diabetic Mice

OBJECTIVE—Podocyte-specific, doxycycline (DOX)-inducible overexpression of soluble vascular endothelial growth factor (VEGF) receptor-1 (sFlt-1) in adult mice was used to investigate the role of the VEGF-A/VEGF receptor (VEGFR) system in diabetic glomerulopathy. RESEARCH DESIGN AND METHODS—We studie...

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Detalles Bibliográficos
Autores principales: Ku, Ching-Hsin, White, Kathryn E., Dei Cas, Alessandra, Hayward, Anthea, Webster, Zoe, Bilous, Rudy, Marshall, Sally, Viberti, Giancarlo, Gnudi, Luigi
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2008
Materias:
Complications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2551695/
https://www.ncbi.nlm.nih.gov/pubmed/18647955
http://dx.doi.org/10.2337/db08-0647

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2551695/
https://www.ncbi.nlm.nih.gov/pubmed/18647955
http://dx.doi.org/10.2337/db08-0647

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