Structural and mechanistic insights into type II trypanosomatid tryparedoxin-dependent peroxidases

TbTDPX (Trypanosoma brucei tryparedoxin-dependent peroxidase) is a genetically validated drug target in the fight against African sleeping sickness. Despite its similarity to members of the GPX (glutathione peroxidase) family, TbTDPX2 is functional as a monomer, lacks a selenocysteine residue and re...

Descripción completa

Detalles Bibliográficos
Autores principales: Alphey, Magnus S., König, Janine, Fairlamb, Alan H.
Formato: Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2552391/
https://www.ncbi.nlm.nih.gov/pubmed/18522537
http://dx.doi.org/10.1042/BJ20080889

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2552391/
https://www.ncbi.nlm.nih.gov/pubmed/18522537
http://dx.doi.org/10.1042/BJ20080889

Ejemplares similares