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Structural and mechanistic insights into type II trypanosomatid tryparedoxin-dependent peroxidases

TbTDPX (Trypanosoma brucei tryparedoxin-dependent peroxidase) is a genetically validated drug target in the fight against African sleeping sickness. Despite its similarity to members of the GPX (glutathione peroxidase) family, TbTDPX2 is functional as a monomer, lacks a selenocysteine residue and re...

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Detalles Bibliográficos
Autores principales:	Alphey, Magnus S., König, Janine, Fairlamb, Alan H.
Formato:	Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2552391/ https://www.ncbi.nlm.nih.gov/pubmed/18522537 http://dx.doi.org/10.1042/BJ20080889

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