The secretion inhibitor Exo2 perturbs trafficking of Shiga toxin between endosomes and the trans-Golgi network

The small-molecule inhibitor Exo2 {4-hydroxy-3-methoxy-(5,6,7,8-tetrahydrol[1]benzothieno[2,3-d]pyrimidin-4-yl)hydraz-one benzaldehyde} has been reported to disrupt the Golgi apparatus completely and to stimulate Golgi–ER (endoplasmic reticulum) fusion in mammalian cells, akin to the well-characteri...

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Detalles Bibliográficos
Autores principales: Spooner, Robert A., Watson, Peter, Smith, Daniel C., Boal, Frédéric, Amessou, Mohammed, Johannes, Ludger, Clarkson, Guy J., Lord, J. Michael, Stephens, David J., Roberts, Lynne M.
Formato: Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2552392/
https://www.ncbi.nlm.nih.gov/pubmed/18522538
http://dx.doi.org/10.1042/BJ20080149

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2552392/
https://www.ncbi.nlm.nih.gov/pubmed/18522538
http://dx.doi.org/10.1042/BJ20080149

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