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Enhanced expressions of microvascular smooth muscle receptors after focal cerebral ischemia occur via the MAPK MEK/ERK pathway

BACKGROUND: MEK1/2 is a serine/threonine protein that phosphorylates extracellular signal-regulated kinase (ERK1/2). Cerebral ischemia results in enhanced expression of cerebrovascular contractile receptors in the middle cerebral artery (MCA) leading to the ischemic region. Here we explored the role...

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Detalles Bibliográficos
Autores principales: Maddahi, Aida, Edvinsson, Lars
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2553085/
https://www.ncbi.nlm.nih.gov/pubmed/18793415
http://dx.doi.org/10.1186/1471-2202-9-85