Virtual screening of GPCRs: An in silico chemogenomics approach

BACKGROUND: The G-protein coupled receptor (GPCR) superfamily is currently the largest class of therapeutic targets. In silico prediction of interactions between GPCRs and small molecules in the transmembrane ligand-binding site is therefore a crucial step in the drug discovery process, which remain...

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Detalles Bibliográficos
Autores principales: Jacob, Laurent, Hoffmann, Brice, Stoven, Véronique, Vert, Jean-Philippe
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2553090/
https://www.ncbi.nlm.nih.gov/pubmed/18775075
http://dx.doi.org/10.1186/1471-2105-9-363

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2553090/
https://www.ncbi.nlm.nih.gov/pubmed/18775075
http://dx.doi.org/10.1186/1471-2105-9-363

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