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Virtual screening of GPCRs: An in silico chemogenomics approach
BACKGROUND: The G-protein coupled receptor (GPCR) superfamily is currently the largest class of therapeutic targets. In silico prediction of interactions between GPCRs and small molecules in the transmembrane ligand-binding site is therefore a crucial step in the drug discovery process, which remain...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2553090/ https://www.ncbi.nlm.nih.gov/pubmed/18775075 http://dx.doi.org/10.1186/1471-2105-9-363 |