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Tactile allodynia can occur in the spared nerve injury model in the rat without selective loss of GABA or GABA(A) receptors from synapses in laminae I–II of the ipsilateral spinal dorsal horn
Although there is evidence that reduced inhibition in the spinal dorsal horn contributes to neuropathic pain, the mechanisms that underlie this are poorly understood. We have previously demonstrated that there is no loss of neurons from laminae I–III in the spared nerve injury (SNI) model [Polgár E,...
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Formato: | Texto |
Lenguaje: | English |
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Elsevier Science
2008
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2553186/ https://www.ncbi.nlm.nih.gov/pubmed/18675320 http://dx.doi.org/10.1016/j.neuroscience.2008.07.009 |