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A Functional Misexpression Screen Uncovers a Role for Enabled in Progressive Neurodegeneration

Drosophila is a well-established model to study the molecular basis of neurodegenerative diseases. We carried out a misexpression screen to identify genes involved in neurodegeneration examining locomotor behavior in young and aged flies. We hypothesized that a progressive loss of rhythmic activity...

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Detalles Bibliográficos
Autores principales: Rezával, Carolina, Berni, Jimena, Gorostiza, Ezequiel Axel, Werbajh, Santiago, Fagilde, María Marta, Fernández, María Paz, Beckwith, Esteban J., Aranovich, Ezequiel J., Sabio y García, Carmen A., Ceriani, María Fernanda
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2553195/
https://www.ncbi.nlm.nih.gov/pubmed/18841196
http://dx.doi.org/10.1371/journal.pone.0003332