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The use of Gene Ontology terms for predicting highly-connected 'hub' nodes in protein-protein interaction networks

BACKGROUND: Protein-protein interactions mediate a wide range of cellular functions and responses and have been studied rigorously through recent large-scale proteomics experiments and bioinformatics analyses. One of the most important findings of those endeavours was the observation that 'hub&...

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Detalles Bibliográficos
Autores principales: Hsing, Michael, Byler, Kendall Grant, Cherkasov, Artem
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2553323/
https://www.ncbi.nlm.nih.gov/pubmed/18796161
http://dx.doi.org/10.1186/1752-0509-2-80