Cargando…
Luminal Mg(2+), A Key Factor Controlling RYR2-mediated Ca(2+) Release: Cytoplasmic and Luminal Regulation Modeled in a Tetrameric Channel
In cardiac muscle, intracellular Ca(2+) and Mg(2+) are potent regulators of calcium release from the sarcoplasmic reticulum (SR). It is well known that the free [Ca(2+)] in the SR ([Ca(2+)](L)) stimulates the Ca(2+) release channels (ryanodine receptor [RYR]2). However, little is known about the act...
| Autores principales: | , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2008
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2553390/ https://www.ncbi.nlm.nih.gov/pubmed/18824590 http://dx.doi.org/10.1085/jgp.200810001 |