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Up-regulation of endothelin type B receptors in the human internal mammary artery in culture is dependent on protein kinase C and mitogen-activated kinase signaling pathways

BACKGROUND: Up-regulation of vascular endothelin type B (ET(B)) receptors is implicated in the pathogenesis of cardiovascular disease. Culture of intact arteries has been shown to induce similar receptor alterations and has therefore been suggested as a suitable method for, ex vivo, in detail deline...

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Detalles Bibliográficos
Autores principales: Nilsson, David, Gustafsson, Lotta, Wackenfors, Angelica, Gesslein, Bodil, Edvinsson, Lars, Paulsson, Per, Ingemansson, Richard, Malmsjö, Malin
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2553399/
https://www.ncbi.nlm.nih.gov/pubmed/18778461
http://dx.doi.org/10.1186/1471-2261-8-21